Wednesday, February 23, 2011

CHOLESTEROL

Cholesterol is an important component for the manufacture of bile acids, steroid hormones, and fat-soluble vitamins including Vitamin A, D, E, K. Although cholesterol is an important and necessary molecule for animals, a high level of serum cholesterol is an indicator for diseases such as heart disease. Cholesterol describe as a waxysteroid metabolite found in the cell membranes and transported in the blood plasma. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. Cholesterol is the principal sterol synthesized by animals, but small quantities are synthesized in other eukaryotes, such as plants ans fungi. It is almost completely absent among prokaryotes, which include bacteria. But everything always have a way. The hydroxyl group on cholesterol interacts with the polar head groups of the membranes phospholipids and sphingolipid, while the bulky steroid and the hydrocarbon chain are embedded in the membrane, alongside the nonpolar fatty acid chain of the other lipids. In this structural role, cholesterol reduces the permeability of the plasma membrane to protons (positive hydrogen ions) and sodium ions. Cholesterol is required to build and maintain membranes too; it regulates membranes fluidity over the range of physiological temperatures. Recently, cholesterol has also been implicated in cell signaling processes, assisting in the formation of lipid rafts in the plasma membrane. In many neurons, a myelin sheath, rich in cholesterol, since it is derived from compacted layers of Schwann cell membrane, provides insulation for more efficient conduction of impulses. Cholesterol also functions in intracellular transport, cell signaling and nerve conduction Within the cell membrane. Cholesterol is essential for the structure and function of invaginated caveolae and clathrin-coated pits, including caveola-dependent and clathrin-dependent endocytosis. The role of cholesterol in such endocytosis can be investigated by using methyl beta cyclodextrin (MβCD) to remove cholesterol from the plasma membrane. Some research indicates that cholesterol may act as an antioxidant. Cholesterol is an important precursor molecule for the synthesis of Vitamin D and the steroid hormones, including the adrenal gland hormones cortisol and aldosterone as well as the sex hormones Progesterone, estrogens, and testosterone, and their derivatives. Within cells, cholesterol is the precursor molecule in several biochemical pathways. In the liver, cholesterol is converted to bile, which is then stored in the gallbladder. Bile contains bile salts, which solubilize fats in the digestive tract and aid in the intestinal absorption of fat molecules as well as the fat-soluble vitamins, Vitamin A, D, E and K. Managed to ensure of new kind virus. And I think it will make an happy for us it called as Human Adenovirus Ad-36. Finded by Wayne State (Detroit), UCLA (LA) and Pennington Biomedical Center (LA), Nutritionist and medical expert in university of Amrica. Ensure as the first virus coused obesity. It etake from a long research with a experimental animals. This virus is isolated firstly from human feces who have been sustained diabetes is atacted enteritis fever and diarrhea. Research show that the Adenovirus Ad-36 visur It have many input as hoarding fat in every inhibited cell. And ability to disrupted the liptine secretion, who responsible with fats metabolism in our body. It caused Fats-hoarding and increase the body absorption ability and increase the blood sugar is well, And over weight finally. This Virus is infected everything and everyone. Dog, chiken, apes san human is certainly. How this virus infected human is still investigated. So far, this virus move from one people to another expected by blood transfusion. Like another kind of infected virus Adenovirus Ad-36 infected virus is incurable. Just a strong antibobdy and superfine health can maintained our healty life. So with this fact, every one is free to eat anything they wan. You can eat ice cream, cheeze, pizza or super big humberger nor hot delicious barbeque. Because what we suold to fight is the virus not the stress nor our food.

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